What Are the Differences Between Botox and Dysport?

What Are the Differences Between Botox and Dysport?

What Are the Differences Between Botox and Dysport?

Both Botox and Dysport are made of highly purified and diluted botulinum toxin derived from Clostridium botulinum cultures. Both are used as medical treatments and to soften fine lines and wrinkles. However, there are some difference between the two.

Dysport is made from a type of botulinum toxin called abobotulinumtoxinA, which is mixed with human serum albumin after it is purified. The solution is then bottled and freeze dried and revived with purified salt water right before it is used. Because of this, Dysport is more diluted and has fewer proteins that regular Botox. This lowers the risk of the patient having an allergic reaction to it, even though allergic reactions are fairly rare. Dysport tends to cover more area than traditional Botox, which makes it good for larger areas of the face such as the forehead. It also means that the dermatologist does not need to use as many syringes as they might need with the thicker and less diluted Botox.


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The FDA approved Dysport for easing the look of glabellar lines that appear between the eyebrows, while Botox was approved to treat crow’s feet and frown lines. Both are used to correct bands in the neck, marionette lines, bunny lines and tiny wrinkles around the lips that are often seen in smokers. Because of its lower protein load and the fact that not as many needles need to be used, Dysport typically causes less swelling and bruising than Botox. It costs somewhat less than Botox and acts more rapidly. On the other hand, Botox is excellent for smaller, thick-muscled areas whose treatment calls for precision.

Dermatologists claim that Dysport lasts longer than regular Botox, though this may be apocryphal. It is true that professionals who use Dysport have to be very knowledgeable when it comes to the musculature and anatomy of their patients’ faces. Dysport as well as Botox must be delivered to the precise muscle in the face to avoid complications such as facial paralysis and blurred vision. These risks are the result of the way the botulinum toxin works. When it is injected, it interrupts a neurotransmitter called acetylcholine, which leads to the paralysis of a muscle. If this muscle is beneath a wrinkle, the wrinkle smooths out.

Administering Dysport and Botox

Both Dysport and Botox are administered by needles that are so fine that most patients don’t need a topical numbing agent on their skin. However, administering a numbing agent, even if it’s only a puff of cold air, is commonly done before the procedure. Each session lasts about 15 to 30 minutes. Botox and Dysport sessions are outpatient procedures and can be done in the office of the clinician or doctor with the patient relaxing in a chair.

In studies where patients had one half of their face treated with Botox and the other with Dysport, it seemed that Dysport reduced the appearance of wrinkles somewhat better than Botox. This was especially true of crow’s feet. The trick to this was the patient scrunching their facial muscles as tightly as they could while they received the injection. When the patient kept their face smooth, there was no difference in Botox and Dysport. On the other hand, some medical professionals claimed that the dosage of Dysport used in these studies was much higher than the dosage of Botox.

Afterwards, the patient rests for a few minutes with an ice pack to soothe their skin and prevent serious bruising. Then, they return to their usual routine. Some people are said to have the treatment done on their lunch hour, but it is a good idea to rest for at least a couple of days afterward. It’s also a good idea for the patient to stay out of the sun for a few days. It is important that the patient not massage the areas where they have received the injections. This can cause the botulinum toxin to spread to places where it is unwanted. Since Dysport spreads out more that Botox, it is important that the areas where it was injected not be rubbed.


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Medical Uses

Botox was used to treat medical conditions before it was used cosmetically. Both Botox and Dysport are used to ease muscle spasms in the neck, elbows, jaw and extremities that are complications of autoimmune diseases such as rheumatoid arthritis as well as the painful neck spasms of cervical dystonia. Other conditions that can be eased with injections of Botox or Dysport are excessive sweating, or hyperhidrosis and spasms in the esophagus, biliary tract, bladder and vocal cords.

If you are a resident of Miami, Florida and environs and are interested in either Dysport or Botox to ease the look of wrinkles and lines, call Dr. Andres Bustillo to set up a consultation. He is a board certified plastic surgeon and a diplomat of both the American Board of Facial Plastic and Reconstructive Surgery and the American Board of Otolaryngology-Head and Neck Surgery.

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